Department of Biophysics

Self-assembly, stability and conductance of amphotericin B channels: bridging the gap between structure and function

Joanna Zielińska, Miłosz Wieczór, Paweł Chodnicki, Ewa Grela, Rafał Luchowski, Łukasz Nierzwicki, Tomasz Bączek, Wiesław I Gruszecki, Jacek Czub

Nanoscale, 2021 | DOI: 10.1039/D0NR07707K

Amphotericin B

Modes of the antibiotic activity of amphotericin B against Candida albicans

Ewa Grela, Agnieszka Zdybicka-Barabas, Bozena Pawlikowska-Pawlega, Malgorzata Cytrynska, Monika Wlodarczyk, Wojciech Grudzinski, Rafal Luchowski & Wieslaw i. Gruszecki

Scientific Reports, 2019 | DOI: 10.1038/s41598-019-53517-3

Electron Microscopy, Cell Surface, Amphotericin B, FLIM

ABCA1 transporter reduces amphotericin B cytotoxicity in mammalian cells

A. Wu, E. Grela, K. Wójtowicz, N. Filipczak, Y. Hamon, R. Luchowski, W. Grudziński, O. Raducka Jaszul, M. Gagoś, A. Szczepaniak, G. Chimini, W. I. Gruszecki, T. Trombik

Cellular and Molecular Life Sciences, 2019 | DOI: 10.1007/s00018-019-03154-w

Amphotericin B, FLIM, Cell Surface, Biomembrane

Mechanism of Binding of Antifungal Antibiotic Amphotericin B to Lipid Membranes: An Insight from Combined Single-Membrane Imaging, Microspectroscopy, and Molecular Dynamics

Ewa Grela, Miłosz Wieczór, Rafał Luchowski, Joanna Zielinska, Angelika Barzycka, Wojciech Grudzinski, Katarzyna Nowak, Piotr Tarkowski, Jacek Czub and Wieslaw I. Gruszecki

Mol. Pharmaceutics 2018, 15, 9, 4202-4213 | DOI: 10.1021/acs.molpharmaceut.8b00572

Amphotericin B, Biomembrane

Imaging of human cells exposed to an antifungal antibiotic amphotericin B reveals the mechanisms associated with the drug toxicity and cell defence

Ewa Grela, Mateusz Piet, Rafal Luchowski, Wojciech Grudzinski, Roman Paduch and Wieslaw I. Gruszecki

Scientific Reports, 2018, 8, 14067 | DOI: 10.1038/s41598-018-32301-9

Amphotericin B, Biomembrane, Cell Surface

Publications